No — there is currently no reliable public source that confirms RuPaul Charles is left-handed.

RuPaul Andre Charles, known mononymously as RuPaul, is an American drag queen, television judge, musician, and model. Born on November 17, 1960, in San Diego, California, he rose to international fame as a drag queen with his hit song "Supermodel (You Better Work)" in 1993.

RuPaul is best known for hosting, producing, and judging the reality competition series "RuPaul's Drag Race," which has garnered multiple Emmy Awards. The show has significantly impacted mainstream culture, popularizing drag and LGBTQ+ issues.

Beyond television, RuPaul has released several studio albums, authored books, and appeared in numerous films and television shows. He is widely considered the most commercially successful drag queen in the United States.

His career spans over four decades, during which he has become an icon for self-acceptance and breaking barriers. RuPaul's influence extends to fashion, music, and pop culture, making him a prominent figure in entertainment.