No — there is no reliable public source currently confirming that Tupac Shakur was left-handed.

Tupac Amaru Shakur, known mononymously as 2Pac, was an American rapper and actor. He is widely regarded as one of the most influential rappers of all time.

Shakur's music often explored themes of poverty, racism, violence, and social issues, drawing from his experiences growing up in disadvantaged urban environments.

He released several critically acclaimed albums during his career, including '2Pacalypse Now,' 'Me Against the World,' and 'All Eyez on Me.' His lyrical prowess and passionate delivery resonated with millions.

Tragically, Tupac Shakur was fatally shot in a drive-by shooting in Las Vegas in 1996 at the age of 25. His legacy continues to influence hip-hop culture and music worldwide.