No — there is no reliable public source currently confirming that Axl Jack Duhamel is left-handed.
Axl Jack Duhamel is the son of American actress and singer Fergie (Stacy Ann Ferguson) and actor Josh Duhamel. Born in 2013, he occasionally appears in photos shared by his celebrity parents.
His parents, Fergie and Josh Duhamel, were married in 2009 and announced their separation in 2017, with their divorce finalized in 2019. Despite their separation, they have maintained an amicable co-parenting relationship for Axl.
Axl Jack Duhamel is not a public figure in his own right, but rather known through his famous parents. Information about his personal life, including handedness, is not typically shared or documented publicly.
As a child, Axl's life is largely kept private by his parents, who aim to provide him with a normal upbringing away from intense media scrutiny.
