No — there is currently no reliable public source that confirms Nancy Guthrie is left-handed.

Nancy Guthrie is a prominent American Bible teacher, author, and speaker known for her work in Christian non-fiction. Her ministry focuses on helping individuals understand and apply biblical truth to their lives, often exploring theological topics with compassion and clarity through her books and teachings.

Guthrie has authored numerous books, including titles like the 'Biblical Theology for Christian Women' series and 'Hearing Jesus Speak into Your Sorrow.' She is recognized for her ability to address challenging subjects, such as grief and suffering, from a deeply biblical perspective.

She also hosts the 'Help Me Teach the Bible' podcast through The Gospel Coalition, where she interviews various Bible scholars and teachers to equip others in their ministries. Her resources are widely utilized by individuals, small groups, and churches worldwide.

Nancy Guthrie and her husband, David, have openly shared their experiences with personal tragedy, which has significantly shaped her ministry, particularly her emphasis on God's sovereignty and comfort in suffering. They founded Respite Retreats for couples who have experienced the death of a child.